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I'm on it for depression as well as fibromyalgia. The way we got around it was a 150 xl dosage with a regular 75 around lunch. I could not tolerate the intense mind numbing effect after day 2 at 300mg. The first 2 months I had great energy and lost a few pounds. The study was published Dec. 5 in the New England Journal of Medicine. i forgot to ask my psych nurse, can i take two 150mg XL instead of the 300 until the 150s are gone, or will this have a different effect? The decision is based on an FDA study that found that the extended release (XL) form of bupropion-- Budeprion XL -- at the 300 milligram (mg) dose was not bioequivalent to brand-name Wellbutrin XL at the same dose, suggesting that it may not be as safe and effective. Wellbutrin can cause a mental fog. So far as how wellbutrin works, last I knew the jury was still out as some of it's affects are not entirely understood. The following additional adverse reactions occurred in controlled trials of bupropion HCl immediate-release (300 to 600 mg per day) at an incidence of at least 1% more frequently than in the placebo group were: cardiac arrhythmia (5% vs. 4%), hypertension (4% vs. 2%), hypotension (3% vs. 2%), menstrual complaints (5% vs. 1%), akathisia (2% vs. 1%), impaired sleep quality (4% vs. 2%), … So yesterday I skipped my wellbutrin, Today I took 150 and left it at that, feeling fine now so I will keep it at 150 for a few more days and try going up again. Fusce dolor tristique. 1) i just switched from 150mg of wellbutrin XL to 300mg. I mentioned to my Dr that I wish I could just take it one a day, so he change me to Wellbutrin XL 300 mg once a day. I started taking Wellbutrin xl 150 when I got seasonal depressive disorder. 6) How Much Does WellButrin XL Cost? Find patient medical information for Wellbutrin XL oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. On day 4 I tried going from 150 to 300 as prescribed. I’ve been on Wellbutrin SR 150 mg 2 x a day for 3 months. I recently started taking Wellbutrin XL (generic). I am in Vibryyd 40 mg every day and it worked great untill Fall, then my anxiety went crazy and I lost motivation. Wellbutrin XL is available in bottles of 30 tablets, 60 tablets or 90 tablets each and in concentrations of 150 mg or 300 mg. I just started this med myself 7 days ago. Comment: I have tried lots of different medicines but I still feel like I haven’t found the right one for me. I take it mainly for ADD but when my do boosted it up to a 300 xl I could feel the brain cells slipping away. No weight changes. We count on the point of view of a lot of clients that already bought Wellbutrin and various other medicines online, so this is the sort of decision you know you are never ever visiting regret. However, the cost may be slightly different based on your insurance coverage. Dr. increased my dosage to 300 mg (today is my first day taking it) and I'm wondering what I could expect as far as side effects at this dosage. Wellbutrin XL is an expensive form of prescription antidepressants. I’m almost done with this 30 days and will be seeing my doctor soon but curious if anyone else had similar experiences as me Wellbutrin XL: Typical starting dosage: 150 mg once daily in the morning. I started on 150mg for the first 15 days and then would do 300mg for the next 15 days. It can likewise be suggested for treating seasonal affective disorder. I was on generic Wellbutrin XL (Budeprion) at 150 mg and didn't have too many side effects - some sleeplessness and headaches at first. 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